发明名称 DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND
摘要 Provided is a compound useful as an inhibitor against the kinase activity of EML4-ALK fusion protein. As a result of intensive and extensive studies on compounds having inhibitory activity against the kinase activity of EMLA-ALK fusion protein, the present inventors found that the diamino heterocyclic carboxamide compounds of the present invention had inhibitory activity against the kinase activity of EML4-ALK fusion protein. By this finding, the present invention was completed. The compounds of the present invention can be used as a pharmaceutical composition for preventing and/or treating cancer, such as lung cancer, non-small cell lung cancer, and small cell lung cancer.
申请公布号 HUE026647(T2) 申请公布日期 2016.07.28
申请号 HUE10772177 申请日期 2010.05.06
申请人 Astellas Pharma Inc.;Kotobuki Pharmaceutical Co., Ltd. 发明人 SHIMADA, Itsuro;KUROSAWA, Kazuo;MATSUYA, Takahiro;IIKUBO, Kazuhiko;KONDOH, Yutaka;KAMIKAWA, Akio;TOMIYAMA, Hiroshi;IWAI, Yoshinori
分类号 A61P35/00 主分类号 A61P35/00
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