Aqueous solution inclusion complexes of benzo-thiophene compounds with water soluble cyclodextrins, and pharmaceutical formulations and methods thereof.

摘要

The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.