发明名称 |
Assay for detection of filariasis using recombinant asparaginyl-tRNA synthetase from the human filrial parasite, Brugia malayi |
摘要 |
Recombinant asparaginyl tRNA synthetase from human filarial parasite Brugia malayi. The enzyme is used in an assay for inhibitors of the synthetase and can be used as an antigen for producing antibody inhibitors of the disease, either monoclonal or polyclonal. The antibodies can be used to detect the synthetase and related enzymes. In particular, the synthetase can be used to produce an antibody to be used for detecting filarial nematodes. The synthetase can be used to produce adenylated nucleosides.
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申请公布号 |
US5846771(A) |
申请公布日期 |
1998.12.08 |
申请号 |
US19970802991 |
申请日期 |
1997.02.21 |
申请人 |
BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY;EUROPEAN MOLECULAR BIOLOGY LABORATORY |
发明人 |
KRON, MICHAEL A.;LEBERMAN, REUBEN |
分类号 |
C12N9/00;(IPC1-7):C12P21/06 |
主分类号 |
C12N9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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