发明名称 |
Novel enterokinase cleavage sequences |
摘要 |
Novel enterokinase cleavage sequences are provided. Also disclosed are methods for the rapid isolation of a protein of interest present in a fusion protein construct including a novel enterokinase cleavage sequence of the present invention and a ligand recognition sequence for capturing the fusion construct on a solid substrate. Preferred embodiments of the present invention show rates of cleavage up to thirty times that of the known enterokinase cleavage substrate (Asp)<SUB>4</SUB>-Lys-Ile. |
申请公布号 |
AU6855901(A) |
申请公布日期 |
2002.01.02 |
申请号 |
AU20010068559 |
申请日期 |
2001.06.19 |
申请人 |
DYAX CORP. |
发明人 |
ARTHUR CHARLES LEY;CHRISTOPHER JON LUNEAU;ROBERT CHARLES LADNER |
分类号 |
G01N33/53;C07K7/06;C07K14/00;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/50;C12N15/09;C12P21/02;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/566 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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