Method for synthesising 2,5-di(hydroxymethyl)furan and 2,5-di(hydroxymethyl)tetrahydrofuran by selective hydrogenation of furan-2,5-dialdehyde

摘要

A method for selective hydrogenation of furan-2,5-dialdehyde (DFF) into 2,5-di(hydroxymethyl)furan (DHMF) and into 2,5-di(hydroxymethyl)tetrahydrofuran (DHMTHF). In relation to the prior art, which uses C6 sugars or 5-hydroxymethyl furaldehyde (5-HMF) as raw materials, the method can be performed at low temperatures (lower than 120° C., preferably 80° C.), while consuming low amounts of catalyst relative to the initial reagent (in particular less than 5%, preferably less than 2% relative to the weight of the reagent). The heterogeneous catalyst used can also be recycled from one reaction to another. Finally, the choice of experimental conditions enables the selective formation of DHMF or DHMTHF.

主权项

1. A process for synthesizing 2,5-di(hydroxymethyl)furan DHMF) and/or 2,5-di (hydroxymethyl) tetrahydrofuran DHMTHF, by bringing into contact:
a) a composition containing furan-2,5-dialdehyde (DFF), b) a protic solvent, c) a source of hydrogen, d) and a hydrogenation catalyst,wherein the composition a) is derived from the oxidation of 5-hydroxymethyl furaldehyde (5-HMF) in the presence of at least an organic acid, a nitroxyl radical, a source of oxygen and an oxygen transfer agent.