发明名称 ANTIBACTERIAL AGENT MEDICAL COMPOUND
摘要 PROBLEM TO BE SOLVED: To provide a novel antibacterial agent that sufficiently exerts antibacterial activity to VRSA as well.SOLUTION: An antibacterial medical compound contains a glycopeptide-based antibacterial compound or pharmaceutically acceptable salt thereof, and a β lactam-based antibacterial compound or pharmaceutically acceptable salt thereof as active ingredients, and exerts synergistic effect by matching in vivo kinetics of the glycopeptide-based antibacterial compound or pharmaceutically acceptable salt thereof, and the β lactam-based antibacterial compound or pharmaceutically acceptable salt thereof. It is preferable that the glycopeptide-based antibacterial compound is vancomycin. It is preferable that the β lactam-based antibacterial compound is a cepham-based antibacterial compound. And it is preferable that the in vivo kinetics is a half-life in blood.SELECTED DRAWING: Figure 6
申请公布号 JP2016210776(A) 申请公布日期 2016.12.15
申请号 JP20160093562 申请日期 2016.05.09
申请人 GENOME SOYAKU KENKYUSHO:KK;UNIV OF TOKYO 发明人 SEKIMIZU KAZUHISA;MATSUMOTO YASUHIKO
分类号 A61K45/06;A61K31/545;A61K38/00;A61P31/04 主分类号 A61K45/06
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