发明名称 |
ANTIBACTERIAL AGENT MEDICAL COMPOUND |
摘要 |
PROBLEM TO BE SOLVED: To provide a novel antibacterial agent that sufficiently exerts antibacterial activity to VRSA as well.SOLUTION: An antibacterial medical compound contains a glycopeptide-based antibacterial compound or pharmaceutically acceptable salt thereof, and a β lactam-based antibacterial compound or pharmaceutically acceptable salt thereof as active ingredients, and exerts synergistic effect by matching in vivo kinetics of the glycopeptide-based antibacterial compound or pharmaceutically acceptable salt thereof, and the β lactam-based antibacterial compound or pharmaceutically acceptable salt thereof. It is preferable that the glycopeptide-based antibacterial compound is vancomycin. It is preferable that the β lactam-based antibacterial compound is a cepham-based antibacterial compound. And it is preferable that the in vivo kinetics is a half-life in blood.SELECTED DRAWING: Figure 6 |
申请公布号 |
JP2016210776(A) |
申请公布日期 |
2016.12.15 |
申请号 |
JP20160093562 |
申请日期 |
2016.05.09 |
申请人 |
GENOME SOYAKU KENKYUSHO:KK;UNIV OF TOKYO |
发明人 |
SEKIMIZU KAZUHISA;MATSUMOTO YASUHIKO |
分类号 |
A61K45/06;A61K31/545;A61K38/00;A61P31/04 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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