发明名称 |
METHODS FOR CRYSTALLIZATION OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE N-CARBOXYANHYDRIDE |
摘要 |
A solution of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine N-carboxyanhydride in a good solvent therefor is added to an aliphatic hydrocarbon solvent to crystallize the N-carboxyanhydride while inhibiting the compound from separating out as an oily matter or scale. An aliphatic hydrocarbon solvent is gradually added to a solution of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine N-carboxyanhydride in a good solvent therefor at a temperature of 60 DEG C or lower over a 1/4 hour or longer to crystallize the N-carboxyanhydride.
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申请公布号 |
WO0187858(A1) |
申请公布日期 |
2001.11.22 |
申请号 |
WO2001JP04059 |
申请日期 |
2001.05.15 |
申请人 |
KANEKA CORPORATION;FUKAE, MASAFUMI;UEDA, YASUYOSHI |
发明人 |
FUKAE, MASAFUMI;UEDA, YASUYOSHI |
分类号 |
C07D263/44;(IPC1-7):C07D263/44 |
主分类号 |
C07D263/44 |
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