VIRUS-LIKE PARTICLE COMPOSITIONS AND VACCINES AGAINST EPSTEIN-BARR VIRUS INFECTION AND DISEASE

摘要

The present iaveatioa relates to prophylactic and/or therapeutic vaccines thatpoatairj Newcastle disease Virus (NDV) vinis-like particles (VLPs) comprising one or mere Epstein- Ban Virus (EBV) antigens, in one embodiment, the invention provides a recombinant vims-iske particle (V'UP) comprising, i is operable combination, a) Neweasile disease virn^ iNDVj matrix (M) protein, and b) one or more Epstein-Barr Virus (BBV ) antigens. The im'eniion's prophylactic and/or therapeutic vacelrses are useful for preventing asd/or treatmg. infection with EBY aixi/or disease associated Epstein-Barr Virus, such as cancer.