| 发明名称 |
Use of Simple Amino Acids to Form Porous Particles |
| 摘要 |
Particles having a tap density of less than 0.4 g/cm3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred particles include a phospholipid, have a median geometric diameter between about 5 and about 30 microns and an aerodynamic diameter between about 1 and about 5 microns. The particles can be formed by spray-drying and are useful for delivery to the pulmonary system. |
| 申请公布号 |
US2016287517(A1) |
申请公布日期 |
2016.10.06 |
| 申请号 |
US201615092799 |
申请日期 |
2016.04.07 |
| 申请人 |
Civitas Therapeutic, Inc. |
发明人 |
Batycky Richard P.;Lipp Michael M.;Niven Ralph W. |
| 分类号 |
A61K9/16;A61K31/685;A61K31/137;A61K9/00 |
主分类号 |
A61K9/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Spray dried particles having a tap density of about 0.4 g/cm3 or less, comprising a therapeutic, prophylactic or diagnostic agent, or any combination thereof, and an amino acid or a salt thereof. |
| 地址 |
Chelsea MA US |
