| 发明名称 | Compositions and methods for non-invasive imaging | ||
| 摘要 | The present invention relates to a novel composition useful in targeted diagnostic and/or therapy of a target site, such as cancerous tissue. The composition and methods disclosed herein find particular use in diagnosing and imaging cancerous tissue. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique. | ||
| 申请公布号 | US9511155(B2) | 申请公布日期 | 2016.12.06 |
| 申请号 | US201314395345 | 申请日期 | 2013.04.17 |
| 申请人 | MERRIMACK PHARMACEUTICALS, INC. | 发明人 | Drummond Daryl C.;Kirpotin Dmitri B.;Wickham Thomas;Hendriks Bart S.;Agresta Samuel;Lee Helen;Gaddy Daniel F. |
| 分类号 | A61K51/12;C07C337/08;A61K51/04 | 主分类号 | A61K51/12 |
| 代理机构 | Honigman Miller Schwartz and Cohn LLP | 代理人 | Honigman Miller Schwartz and Cohn LLP ;Bott Cynthia M.;O'Brien Jonathan P. |
| 主权项 | 1. A liposomal imaging agent composition comprising: (a) liposomes in a pharmaceutically acceptable medium, said liposomes each having an interior space and a membrane separating said interior from said medium, said membrane comprising one or more lipids; and (b) a compound comprising a chelated metal ion, M, as shown in formula (II) in at least one liposome of the liposomes of (a):in which M is a copper cation detectable within the liposomal imaging agent. | ||
| 地址 | Cambridge MA US | ||