摘要 |
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, wherein X1, X2, R1, R7, R8 and R9 are as herein described. The present invention also provides pharmaceutical compositions comprising these compounds and methods for their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula (I) in the treatment of Btk mediated disorders. |
申请人 |
MERCK SHARP & DOHME CORP.;SIU, Tony;ALTMAN, Michael, D.;ANDRESEN, Brian, M.;LIU, Jian;KOZLOWSKI, Joseph;BOGA, Sobhana Babu;YU, Younong;ANAND, Rajan;CAI, Jiaqiang;WANG, Dahai;LIU, Shilan |
发明人 |
SIU, Tony;ALTMAN, Michael, D.;ANDRESEN, Brian, M.;LIU, Jian;KOZLOWSKI, Joseph;BOGA, Sobhana Babu;YU, Younong;ANAND, Rajan;CAI, Jiaqiang;WANG, Dahai;LIU, Shilan |