发明名称 INDAZOLE AND AZAINDAZOLE BTK INHIBITORS
摘要 The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, wherein X1, X2, R1, R7, R8 and R9 are as herein described. The present invention also provides pharmaceutical compositions comprising these compounds and methods for their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula (I) in the treatment of Btk mediated disorders.
申请公布号 WO2016164285(A1) 申请公布日期 2016.10.13
申请号 WO2016US25809 申请日期 2016.04.04
申请人 MERCK SHARP & DOHME CORP.;SIU, Tony;ALTMAN, Michael, D.;ANDRESEN, Brian, M.;LIU, Jian;KOZLOWSKI, Joseph;BOGA, Sobhana Babu;YU, Younong;ANAND, Rajan;CAI, Jiaqiang;WANG, Dahai;LIU, Shilan 发明人 SIU, Tony;ALTMAN, Michael, D.;ANDRESEN, Brian, M.;LIU, Jian;KOZLOWSKI, Joseph;BOGA, Sobhana Babu;YU, Younong;ANAND, Rajan;CAI, Jiaqiang;WANG, Dahai;LIU, Shilan
分类号 A61K31/55;A61K31/501;A61K31/506 主分类号 A61K31/55
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