Collagen peptide composition production method, DPP-4 inhibitor, and antihyperglycemic agent

摘要

Provided are methods of producing a novel collagen peptide composition, and a DPP-4 inhibitor and antihyperglycemics that comprise the above-mentioned collagen peptide composition. Ginger rhizome-derived enzymes are added to and break down a collagen and/or gelatin solution to generate peptide compositions comprising peptides represented by X-Hyp-Gly (wherein X represents an amino acid residue other than Gly, Hyp, and Pro). The thus obtained collagen peptide composition has a high DPP-4 inhibitory activity and an excellent antihyperglycemic effect.

主权项

1. A method of producing a collagen peptide composition comprising degrading a collagen, a gelatin, or a combination thereof by adding a ginger rhizome-derived enzyme and a reducing agent containing an SH group to the collagen, gelatin, or combination thereof, solution,
wherein the degradation of the collagen, the gelatin, or the combination thereof, produces a collagen peptide composition comprising a peptide represented by X-Hyp-Gly wherein X represents an amino acid residue other than Gly, Hyp, or Pro.