发明名称 |
NOVEL EGFR BINDING PROTEINS |
摘要 |
The present invention relates to new EGFR binding molecules based on ubiquitin muteins (Affilin®), preferably Affilin molecules having a characteristic three amino acid residue motif. The invention further refers to EGFR binding molecules that bind to different or non-overlapping epitopes than the anti-EGFR monoclonal antibody Cetuximab. The invention further relates to the use of these EGFR binding proteins in medicine, preferably for use in the diagnosis or treatment of cancer. |
申请公布号 |
WO2016124702(A1) |
申请公布日期 |
2016.08.11 |
申请号 |
WO2016EP52408 |
申请日期 |
2016.02.04 |
申请人 |
SCIL PROTEINS GMBH |
发明人 |
BOSSE-DOENECKE, EVA;SETTELE, FLORIAN;FIEDLER, ERIKE;HAUPTS, ULRICH |
分类号 |
C07K14/71;C12N15/10 |
主分类号 |
C07K14/71 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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