发明名称 |
ENTERIC-COATED PREPARATION |
摘要 |
<p>Disclosed is an enteric-coated preparation comprising, as an active ingredient, a therapeutic agent for thrombosis or the like which has a potent inhibitory activity on thrombin, particularly [(S)-1-[(S)-2-[(trans-4-aminocyclohexylmethyl) carbamoyl]pyrrolidine-1-carbonyl]-2-isopropylthio-2- methylpropyl]carbamic acid propyl ester or a pharmaceutically acceptable salt thereof. The preparation is hardly susceptible to the influence of diets, can be administered at a dose frequency of once a day, exerts an effectiveness as a therapeutic agent for thrombosis or the like when orally administered, and has excellent pharmacokinetic properties.</p> |
申请公布号 |
WO2007049587(A1) |
申请公布日期 |
2007.05.03 |
申请号 |
WO2006JP321119 |
申请日期 |
2006.10.24 |
申请人 |
MITSUBISHI PHARMA CORPORATION;NOGUCHI, TETSURO;TAKEI, KOJI |
发明人 |
NOGUCHI, TETSURO;TAKEI, KOJI |
分类号 |
A61K9/16;A61K31/401;A61K9/28;A61K47/32;A61K47/38;A61P7/02 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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