NOVEL PROLIFERATION MARKER IN PAPILLARY THYROID CARCINOMA AND NOVEL METHOD OF DIAGNOSIS DETECTING THE MARKER

摘要

An MCM3(minichromosome maintenance protein 3) is provided to diagnose papillary thyroid carcinoma(PTC) effectively and accurately at the early stage. A method for diagnosing PTC comprises the steps of: (a) providing a tissue sample obtained from an individual; (b) contacting the sample with a diagnosis reagent forming a specific bond to an MCM3; and (c) identifying formation of a complex between the MCM3 and the diagnosis reagent to diagnose the PTC. A kit for diagnosing the PTC comprises the diagnosis reagent forming the specific bond to the MCM3 and a detection marker. A marker for diagnosing the PTC consists of the MCM3. Further, the kit for diagnosing the PTC additionally comprises a second antibody such as immunoglobulin G.