| 发明名称 |
NOVEL FARNESOID X RECEPTOR (FXR) (NR1H4) BINDING AND ACTIVITY MODULATING COMPOUNDS |
| 摘要 |
The invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds. |
| 申请公布号 |
EA024083(B1) |
申请公布日期 |
2016.08.31 |
| 申请号 |
EA20120090047 |
申请日期 |
2010.08.19 |
| 申请人 |
PHENEX PHARMACEUTICALS AG |
发明人 |
KREMOSER CLAUS;ABEL ULRICH;STEENECK CHRISTOPH;KINZEL OLAF |
| 分类号 |
C07D249/06;A61K31/4192;A61K31/42;A61K31/443;A61K31/4439;A61P1/16;A61P3/10;A61P35/00;C07D261/08;C07D413/04;C07D413/12;C07D413/14 |
主分类号 |
C07D249/06 |
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