| 发明名称 |
SMALL MOLECULE COMPOUNDS TARGETING PBX1 TRANSCRIPTIONAL COMPLEX |
| 摘要 |
In accordance with one or more embodiments, the present invention provides a compound of formulas I, II, and III, for use in methods of inhibition of PBX1-DNA interaction in a mammalian cell or population of cells, and for use in the treatment of medical conditions including but not limited to cancers, developmental disorders, inflammatory disorders, autoimmune diseases, or neuro-degenerative disorders. |
| 申请公布号 |
WO2016172437(A2) |
申请公布日期 |
2016.10.27 |
| 申请号 |
WO2016US28782 |
申请日期 |
2016.04.22 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
WANG, Tian-Li;SHIH, Ie-Ming;VAAL, Mark;STOECK, Alexander;JUNG, Jin G. |
| 分类号 |
C07D215/16;A61K31/47;A61K31/4706;A61P25/00;A61P29/00;C07D215/20 |
主分类号 |
C07D215/16 |
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