发明名称 BISPECIFIC ANTIBODIES FOR RETARGETING ANTICANCER CYTOTOXIC LYMPHOCYTES AND HYBRIOMAS AND MONOCLONAL ANTIBODIES THEREFORE
摘要 <p>A bispecific antibody has binding specificity for a marker common to all prostate cells on one arm of the antibody, and binding specificity for T cell marker CD3 on the other antibody arm. The combined specificities bring together a tumor cell and a T effector cell, whose specificity is reprogrammed to kill the tumor cell. In vitro studies showed that the bispecific antibody achieves a much greater level of cytotoxicity than either individual antibody alone.</p>
申请公布号 WO1999067359(A2) 申请公布日期 1999.12.29
申请号 US1999013713 申请日期 1999.06.17
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