发明名称 EFFERVESCENT COMPOSITIONS CONTAINING N-ACETYLCYSTEINE
摘要 Effervescent pharmaceutical compositions containing a high amount of N-acetylcysteine and a method of treating acetaminophen poisoning with effervescent pharmaceutical compositions containing a high amount of N-acetylcysteine are described.
申请公布号 US2016331710(A1) 申请公布日期 2016.11.17
申请号 US201615222232 申请日期 2016.07.28
申请人 ALPEX PHARMA S.A. 发明人 STROPPOLO Federico;GRANATA Gabriele;ARDALAN Shahbaz S.
分类号 A61K31/198;A61K9/46;A61K47/26;A61K47/12;A61K9/00;A61K47/02 主分类号 A61K31/198
代理机构 代理人
主权项 1. A method of treating acetaminophen poisoning comprising administering an effective amount of an oral effervescent composition comprising at least 50% w/w of Nacetylcysteine, at least 20% w/w of a carbonate or bicarbonate salt, and from 3.5 to 15% w/w of a mixture of pharmaceutically acceptable excipients comprising a sweetener, a flavorant, and a diluent, wherein the oral effervescent composition is in an unit dose of Nacetylcysteine selected from the group consisting of 0.5 g, 1.0 g, 1.5 g, 2.0 g and 2.5 g.
地址 Mezzovico CH