发明名称 Synthesis of [1-13C]pyruvic acid], [2-13C]pyruvic acid], [3-13C]pyruvic acid] and combinations thereof
摘要 The present invention is directed to the labeled compounds, wherein C* is each either 13C and 12C where at least one C* is 13C, each hydrogen of the methylene group is hydrogen or deuterium, the methyl group includes either zero or three deuterium atoms, Q is sulfide, sulfinyl, or sulfone, Z is an aryl group such as 1-naphthyl, substituted 1-naphthyl, 2-naphthyl, substituted 2-naphthyl, or a phenyl group wherein R1, R2, R3, R4 and R5 are each independently either hydrogen, a C1-C4 lower alkyl, a halogen, and an amino group such as NH2, NHR and NRR' where R and R' are each independently either a C1-C4 lower alkyl, a phenyl, and an alkoxy group, and the methyl group can include either zero or three deuterium atoms. The present invention is also directed to the labeled compounds
申请公布号 US2009030232(A1) 申请公布日期 2009.01.29
申请号 US20080220234 申请日期 2008.07.22
申请人 MARTINEZ RODOLFO A;UNKEFER CLIFFORD J;ALVAREZ MARC A 发明人 MARTINEZ RODOLFO A.;UNKEFER CLIFFORD J.;ALVAREZ MARC A.
分类号 C07C321/02;C07C237/40 主分类号 C07C321/02
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