1α,25-DIHYDROXY-24,24-DIFLUORO-19-NOR-VITAMIN D3 ANALOGS AND THEIR PHARMACEUTICAL USES
摘要
Disclosed are la,25-dihydroxy-24,24-difluoro-2-methylene-19-nor- vitamin D analogs of formula I and their pharmaceutical uses. These new vitamin D analogs are 19-nor-vitamin D analogs having two fluorine atom substitutions at the 24 position (C-24) in the side chain and optionally having a 2-methylene substituent.
申请公布号
WO2016191583(A1)
申请公布日期
2016.12.01
申请号
WO2016US34392
申请日期
2016.05.26
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;DELUCA, Hector, F.;FLORES, Agnieszka;PLUM, Lori, A.;HOLDEN, Hazel;THODEN, James
发明人
DELUCA, Hector, F.;FLORES, Agnieszka;PLUM, Lori, A.;HOLDEN, Hazel;THODEN, James