Inducible endothelial surface protein mediating melanoma cell adhesion, antibodies, and uses

摘要

Monoclonal antibody E1/6, or fragments thereof, blocks adhesion to the vascular endothelium of certain pathophysiological cells. Monoclonal antibody E1/6, or fragments thereof, and the glycoprotein recognized by the E1/6 antibody, are used pharmaceutically, therapeutically, and diagnostically in the treatment of these pathophysiological disorders. Compositions, methods of treating, and methods of diagnosing are disclosed.