发明名称 Novel pyridine derivatives and pyrimidine derivatives (3)
摘要 A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH-, nitrogen or the like.]
申请公布号 US2008319188(A1) 申请公布日期 2008.12.25
申请号 US20060508322 申请日期 2006.08.23
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 MATSUSHIMA TOMOHIRO;TAKAHASHI KEIKO;FUNASAKA SETSUO;OBAISHI HIROSHI;SHIROTORI SHUJI
分类号 C07D213/72;C07D239/47;C07D401/02;C07D403/02;C07D413/02;C07D417/02 主分类号 C07D213/72
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