发明名称 |
Using allosteric hemoglobin modifiers to decrease oxygen affinity in blood |
摘要 |
A compound has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compound is capable of acting on hemoglobin in whole blood. In addition, the compound can maintain the oxygen affinity in blood during storage and can restore the oxygen affinity of outdated blood.
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申请公布号 |
EP1468680(A2) |
申请公布日期 |
2004.10.20 |
申请号 |
EP20040009908 |
申请日期 |
1992.05.19 |
申请人 |
VIRGINIA COMMONWEALTH UNIVERSITY |
发明人 |
ABRAHAM, DONALD J.;MEHANNA, AHMED;MAHRAN, MONA;RANDAD, RAMNARAYAN |
分类号 |
A61K31/215;A61K31/19;A61K31/192;A61K31/195;A61K31/325;A61K31/40;A61K31/403;A61K31/4035;A61P7/00;A61P9/00;A61P43/00;C07C233/29;C07C233/73;C07C235/38;C07C271/58;C07D209/48;(IPC1-7):A61K31/192 |
主分类号 |
A61K31/215 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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