| 发明名称 |
SUBSTITUTED 1H-PYRROLO [2,3-B]PYRIDINE AND 1H-PYRAZOLO [3, 4-B]PYRIDINE DERIVATIVES AS SALT INDUCIBLE KINASE 2 (SIK2) INHIBITORS |
| 摘要 |
The present invention relates to compounds according to Formulas I, IA or IB: to pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes. |
| 申请公布号 |
EP2931722(A4) |
申请公布日期 |
2016.09.21 |
| 申请号 |
EP20130862263 |
申请日期 |
2013.12.10 |
| 申请人 |
ARRIEN PHARMAEUTICALS LLC |
发明人 |
VANKAYALAPATI, HARIPRASAD;YERRAMREDDY, VENKATAKRISHNAREDDY;GANIPISETTY, VENU, BABU;TALLURI, SURESHKUMAR;APPALANENI, RAJENDRA, P. |
| 分类号 |
A61K31/437;A61K31/444;A61K31/4545;A61K31/496;A61K31/5377;A61K31/635;A61P9/00;A61P35/00;C07D471/04 |
主分类号 |
A61K31/437 |
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