发明名称 |
BIORESORBABLE CONTROLLED-RELEASE COMPOSITION |
摘要 |
A novel method for the preparation of a highly densified and at least partly, preferably fully or almost fully hydrated ceramic for use in the preparation of a pharmaceutical composition notably for controlled-release of one or more therapeutically, prophylactically and/or diagnostically active substance. The method involves a concomitant step of hydrating and densifying a bioresorbable and hydratable ceramic such as calcium sulphate. The invention also relates to compositions comprising such a highly densified ceramic. The pharmaceutical composition is useful for targeted and controlled local prolonged release of active substances, e.g. anti-cancer agents, whereby the spectrum and severity of side effects are minimized due to an optimized local concentration-time profile. |
申请公布号 |
WO2007104549(A2) |
申请公布日期 |
2007.09.20 |
申请号 |
WO2007EP02250 |
申请日期 |
2007.03.14 |
申请人 |
LIDDS AB;AXEN, NIKLAS;LENNERHAES, HANS |
发明人 |
AXEN, NIKLAS;LENNERHAES, HANS |
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