| 摘要 |
<p>A multi-valent vaccine composition is described comprising a conjugate of the capsular polysaccharide of H. influenzae b not adsorbed onto an aluminium adjuvant salt, and two or more further bacterial polysaccharides. A multi-valent vaccine composition is also described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, Hepatitis B surface antigen, a conjugate of the capsular polysaccharide of H. influenzae b, and a conjugate of a capsular polysaccharide of N. meningitidis type A or C (or both). Furthermore, a multi-valent vaccine composition is described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, and a low dose of a conjugate of the capsular polysaccharide of H. influenzae b.</p> |
| 申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
BOUTRIAU, DOMINIQUE;CAPIAU, CARINE;DESMONS, PIERRE MICHEL;LEMOINE, DOMINIQUE;POOLMAN, JAN |
