Microfluidic device and method of manufacturing the microfluidic device

摘要

A microfluidic device having a substrate with an array of curvilinear cavities. The substrate of the microfluidic device is preferably fabricated of a polymer such as polydimethylsiloxane (PDMS). The microfluidic device is manufactured using a gas expansion molding (GEM) technique.

主权项

1. A microfluidic device comprising:
a substrate comprising a first surface on one side of the substrate, a second surface on an opposite side of the substrate and a plurality of curvilinear spherical cavities formed in said substrate between the first and second surfaces, each of said plurality of curvilinear spherical cavities comprising an inner surface and an opening at the first surface to an exterior of the substrate, the opening having a first diameter, wherein the inner surface of each curvilinear spherical cavity curves outward from a rounded bottom located at a point furthest from said opening of said cavity to a maximum diameter, and then curves inward from said maximum diameter to said opening at the first surface, said maximum diameter being greater than said first diameter, and wherein material separating adjacent curvilinear spherical cavities consists essentially of the substrate.