发明名称 |
OPTICAL SELECTION OF CELLS |
摘要 |
Provided herein are photochemical crosslinkers and photocleavable crosslinkers and their uses in methods for cell selection from cell cultures. The photochemical crosslinkers comprise a fluorescent dye and a radical generator. The photocleavable crosslinkers comprise a photocleavable linker linking two electrophilic groups to each other. Also provided are systems for imaging cells comprising a plurality of cells crosslinked to extracellular matrix proteins using a crosslinker as described, an imaging apparatus, an illuminating apparatus, and software for image processing. |
申请公布号 |
US2016208308(A1) |
申请公布日期 |
2016.07.21 |
申请号 |
US201614995716 |
申请日期 |
2016.01.14 |
申请人 |
President and Fellows of Harvard College |
发明人 |
Cohen Adam E.;Chien Miao-Ping |
分类号 |
C12Q1/24;G01N21/64;G01N33/58;C07D207/46;C07D495/04 |
主分类号 |
C12Q1/24 |
代理机构 |
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代理人 |
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主权项 |
1. A photochemical crosslinker comprising a fluorescent dye and a radical generator. |
地址 |
Cambridge MA US |