| 主权项 |
1. A compound of Formula (I) wherein A denotes a 5- to 7-membered saturated carbocyclic ring wherein 1 —CH2— group is optionally replaced by an oxygen atom; R1 and R1′ are each independently selected from halogen, CF3, and C1-C6-alkyl which is optionally substituted with one to 3 Hal, C1-C6-alkoxy, CN, C1-C6-alkyl sulfonyl and amine; Q is selected from a —NR4—, —(CH2)NR4CO—, —NR4CO—, and —CONR4—; Z is CH or N, R2 is a 5- to 6-membered unsaturated or aromatic heterocyclic ring containing 1 to 3 heteroatoms independently selected from O, N or S, and which is optionally substituted with 1 to 3 groups independently selected from C1-C6-alkyl, and C1-C6 alkoxy, R3 is H, C1-C6-alkoxy, CN, or halogen; and each R4 is independently H or C1-C6-alkyl; and pharmaceutically acceptable solvates, tautomers, salts, hydrates and stereoisomers thereof, including mixtures thereof in all ratios. |
