发明名称 |
Systems and methods for comprehensive analysis of molecular profiles across multiple tumor and germline exomes |
摘要 |
Omics patient data are analyzed using sequences or diff objects of tumor and matched normal tissue to identify patient and disease specific mutations, using transcriptomic data to identify expression levels of the mutated genes, and pathway analysis based on the so obtained omic data to identify specific pathway characteristics for the diseased tissue. Most notably, many different tumors have shared pathway characteristics, and identification of a pathway characteristic of a tumor may thus indicate effective treatment options ordinarily not considered when tumor analysis is based on anatomical tumor type only. |
申请公布号 |
IL249259(D0) |
申请公布日期 |
2016.12.29 |
申请号 |
IL20160249259 |
申请日期 |
2016.11.28 |
申请人 |
JOHN ZACHARY SANBORN;NANT HOLDINGS IP LLC;NANTOMICS LLC;STEPHEN CHARLES BENZ;SHAHROOZ RABIZADEH;PATRICK SOON-SHIONG;CHARLES JOSEPH VASKE |
发明人 |
JOHN ZACHARY SANBORN;STEPHEN CHARLES BENZ;SHAHROOZ RABIZADEH;PATRICK SOON-SHIONG;CHARLES JOSEPH VASKE |
分类号 |
G06F |
主分类号 |
G06F |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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