发明名称 Opioid Antagonist Formulations
摘要 In certain embodiments, the present invention is directed to a solid controlled-release dosage form comprising a core comprising a core portion of an opioid antagonist and a shell encasing the core and comprising a shell portion of the opioid antagonist, wherein the release profile of the core portion of opioid antagonist is different than the release profile of the shell portion of opioid antagonist.
申请公布号 US2016243107(A1) 申请公布日期 2016.08.25
申请号 US201415030709 申请日期 2014.12.22
申请人 PURDUE PHARMA L.P. 发明人 Moline Margaret
分类号 A61K31/485;A61K9/24;A61K9/20 主分类号 A61K31/485
代理机构 代理人
主权项 1. A solid controlled-release dosage form comprising a core comprising a core portion of an opioid antagonist and a shell encasing the core and comprising a shell portion of the opioid antagonist, wherein a release profile of the core portion of opioid antagonist is different than the release profile of the shell opioid antagonist.
地址 Stamford CT US