| 发明名称 |
METHOD OF MAKING PARTICLES FOR USE IN A PHARMACEUTICAL COMPOSITION |
| 摘要 |
The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable for the promotion of the dispersal of the composite active particles upon actuation of an inhaler. The invention also relates to compositions for inhalation prepared by the method. |
| 申请公布号 |
US2016243046(A1) |
申请公布日期 |
2016.08.25 |
| 申请号 |
US201615079171 |
申请日期 |
2016.03.24 |
| 申请人 |
VECTURA LIMITED |
发明人 |
STANIFORTH JOHN NICHOLAS;GREEN MATTHEW MICHAEL;MORTON DAVID ALEXANDER VODDEN |
| 分类号 |
A61K9/51;A61K31/137;A61K9/00 |
主分类号 |
A61K9/51 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Composite active particles for use in a pharmaceutical composition for pulmonary administration, each composite active particle comprising a particle of active material and particles of an additive material on the surface of the particle of active material, the composite active particles having a mass median aerodynamic diameter of not more than 10 μm, wherein the additive material comprises a metal stearate. |
| 地址 |
Wiltshire GB |
