| 发明名称 |
MULTILAYERED BONE GRAFT AND METHOD OF MAKING SAME |
| 摘要 |
A synthetic bone graft is described which is adapted to be received within a bone defect and which is structurally load-bearing. The bone graft comprises an entirely synthetic graft body corresponding in shape and size to the bone defect. The graft body is composed of a plurality of superimposed multilayered structures, each of the multilayered structures having a biopolymer layer joined to a biomineral layer to define an interface therebetween. The biomineral layer has a stiffness that is greater than that of the biopolymer layer, and the biopolymer layer has a toughness that is less than that of the biomineral layer. |
| 申请公布号 |
US2016235536(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201615044414 |
申请日期 |
2016.02.16 |
| 申请人 |
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY |
发明人 |
BARTHELAT Francois;TANZER Michael;CAVELIER Sacha |
| 分类号 |
A61F2/28;A61L27/12;A61L27/22;A61L27/02;B29C67/24;A61L27/24 |
主分类号 |
A61F2/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A synthetic bone graft adapted to be received within a bone defect, the bone graft comprising an entirely synthetic graft body corresponding in shape and size to the bone defect and being structurally load-bearing, the graft body being composed of a plurality of superimposed multilayered structures, each of said multilayered structures having a biopolymer layer joined to a biomineral layer to define an interface therebetween, wherein the biomineral layer has a stiffness that is greater than that of the biopolymer layer, and the biopolymer layer has a toughness that is less than that of the biomineral layer. |
| 地址 |
Montreal CA |
