| 发明名称 |
NANO-TYPE LACTIC ACID BACTERIUM |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a lactic acid bacterium having a favorable particle diameter for Th1 induction, excellent in the productivity of INF-α, and excellent in dispersibility in water. <P>SOLUTION: A bacterial cell of a nano-type lactic acid bacterium is obtained by adjusting a pH in a medium in a culturing step and a processing step of the lactic acid bacterium to a neutral range, wherein a mode value in a particle size distribution is 1.0 μm or less and the lactic acid bacterium is lactobacillus brevis. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2012229258(A) |
申请公布日期 |
2012.11.22 |
| 申请号 |
JP20120160372 |
申请日期 |
2012.07.19 |
| 申请人 |
SHINWA YAKUHIN KK;BIO KEN:KK;JAPANESE ASSOCIATION OF CLINICAL RESEARCH ON SUPPLEMENTS;COSMO SHOKUHIN KK |
发明人 |
HASEGAWA HIDEO;SUGA TATSUHIKO |
| 分类号 |
A61K35/74;A23K1/16;A23L1/30;A61K8/99;A61P37/04;C12N1/20 |
主分类号 |
A61K35/74 |
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