发明名称 |
Method of screening multiple single nucleotide polymorphisms associated with susceptibility to specific disease or drug response |
摘要 |
Provided is a method of screening multiple single nucleotide polymorphisms (SNPs) having significance with a case group, the method comprising: selecting one or more SNPs from nucleic acid sequences of the case group and a control group; generating all combinable genotype patterns of multiple SNPs comprised of two or more of the selected SNPs; determining frequencies of the genotype patterns from the case group and the control group; and determining and choosing genotype patterns having statistical significance with the case group using the frequencies. According to the method of screening multiple SNPs, multiple SNPs associated with a specific disease or drug can be effectively selected from the entire genome of an individual. Methods of identifying susceptibility of an individual to development of Type II diabetes are also disclosed.
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申请公布号 |
US2006286589(A1) |
申请公布日期 |
2006.12.21 |
申请号 |
US20060454336 |
申请日期 |
2006.06.16 |
申请人 |
NAM YUN-SUN;CHOI SEUNG-HAK;KIM JAE-HEUP |
发明人 |
NAM YUN-SUN;CHOI SEUNG-HAK;KIM JAE-HEUP |
分类号 |
C12Q1/68;G06F19/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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