发明名称 CONSTRUCTION AND USE OF TRANSFECTION ENHANCER ELEMENTS
摘要 Nucleic acids comprising a nucleic acid moiety and two or more transfection enhancer elements (TEE's) according to the general formula (I): Hydrophobic moiety-pH-responsive hydrophilic moiety, wherein said pH sensitive hydrophilic moiety of said TEE is independently a weak acid having a pka of between 4 and 6.5 or is a zwitterionic structure comprising a combination of acidic groups with weak basis having a pKa of between 4.5 and 7.
申请公布号 US2010022621(A1) 申请公布日期 2010.01.28
申请号 US20070448452 申请日期 2007.12.19
申请人 PANZNER STEFFEN 发明人 PANZNER STEFFEN
分类号 A61K31/711;A61K31/7088;A61K31/7105;A61P35/00;A61P37/06;C12N15/74 主分类号 A61K31/711
代理机构 代理人
主权项
地址