TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES

摘要

The present invention relates to isolated polypeptides which are capable of inhibiting the activation of the complement system and the use of such polypeptides for the treatment of autoimmune and/or inflammatory diseases such as rheumatoid arthritis, osteoarthritis, atherosclerosis, respiratory distress syndrome, obstructive lung disease, glomerulonephritis, ischemia/reperfusion injury or multiple sclerosis. Preferably, the isolated peptides are fragments of fibromodulin.