PTH FORMULATIONS AND METHODS OF USE

摘要

What is described is an aqueous pharmaceutical formulation of PTH, comprising a therapeutically effective amount of PTH(l-34) and one or more excipients selected from the group consisting of a solubilizing agent, a chelating agent, one or more polyols, and a nonionic surface active agent, a method of using such formulation for treating osteoporosis in a mammal by intranasal administration, and use of PTH(I -34) in the manufacture of such formulation for treating osteoporosis in a mammal.