发明名称 Azetidinium-containing copolymers and uses thereof
摘要 The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
申请公布号 US9422447(B2) 申请公布日期 2016.08.23
申请号 US201313913734 申请日期 2013.06.10
申请人 Novartis AG 发明人 Holland Troy Vernon;Chang Frank;Qiu Yongxing;Pruitt John Dallas;Chiang Chung-Yuan;Shankernarayanan Manivakkam J.;Scott Robert;Kapoor Yash
分类号 C09D139/04;C08F20/00;C08F26/00;B29D11/00 主分类号 C09D139/04
代理机构 代理人 Zhou Jian
主权项 1. An azetidinium-containing vinylic monomer, being represented by formula (2) in which: R″ is hydrogen or methyl;p1, p2, and p3 independent of one another are zero or 1;Y4 is a linkage selected from the group consisting of a direct bond, —O—, —NR′—, —C(O)—NR′—, —NR′—C(O)—, —O—C(O)—NH—, —NH—C(O)—O—, —NR′—C(O)—NH—, —NH—C(O)NR′—, —C(O)—O—, —O—C(O)—, R′ is hydrogen, a C1-C20 unsubstituted or substituted, linear or branched alkyl group;Z4, is a direct bond, a C1-C20 unsubstituted or substituted, linear or branched alkylene divalent radical optionally containing therein one or more linkages of —O—, —NR′—, and —C(O)—, a C1-C7 alkyleneoxy C1-C7 alkylene divalent radical, or a divalent radical of —(CH(R″)CH2O)r1—CH(R″)CH2— in which R″ is as defined above and r1 is an integer of 1 to 20; andZ5 is a C1-C20 unsubstituted or substituted, linear or branched alkyl group, —(CH2)r2—O—(CH2CH2O)r1—Z6 in which r1 is as defined above, r2 is zero or an integer of 1 to 7, andZ6 is a C1-C5 alkyl.
地址 Basel CH
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