发明名称 METABOLICALLY ACTIVATED RECOMBINANT VIRAL VECTORS AND METHODS FOR THEIR PREPARATION AND USE
摘要 Recombinant viral vectors, especially parvovirus vectors such as adeno-associated virus (AAV) vectors, capable of enhanced expression of heterologous sequences, and methods for their construction and use, are provided. The vectors have a structure, or are capable of rapidly adopting a structure, which involves intrastrand base pairing of at least one region in a heterologous sequence.
申请公布号 US2016168589(A1) 申请公布日期 2016.06.16
申请号 US201514804177 申请日期 2015.07.20
申请人 Genzyme Corporation 发明人 CARTER Barrie J.
分类号 C12N15/86;C07K16/00;C07K14/705 主分类号 C12N15/86
代理机构 代理人
主权项
地址 Cambridge MA US