| 摘要 |
The invention involves a method for preventing hepatic injury or liver cell death associated with certain liver diseases in a mammal comprising administering to the mammal an effective amount of an antagonist to activin, optionally in combination with other antagonists to hepatocytoxic proteins such as TGF- beta . An example of a suitable liver disease is one caused by a viral infection such as hepatitis or an autoimmune disease. Bispecific molecules targeting both activin and TGF- beta are also disclosed. |
