发明名称 |
RIBOFLAVIN FOR THE TREATMENT OF ISCHEMIC STROKE AND/OR OTHER GLUTAMATE EXCITOTOXICITY-ASSOCIATED DISEASES |
摘要 |
The present invention relates to a combination therapy comprising the use of riboflavin and oxaloacetate. Specifically, it is directed to new compositions, pharmaceutical compositions, kits of parts and methods for treating ischemic stroke and/or other excitotoxicity-associated diseases. It further relates to riboflavin for use in the therapeutic treatment of acute ischemic stroke by intravascular administration within the first twelve hours of symptom onset. |
申请公布号 |
WO2016177840(A1) |
申请公布日期 |
2016.11.10 |
申请号 |
WO2016EP60104 |
申请日期 |
2016.05.04 |
申请人 |
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA;SERVIZO GALEGO DE SAÚDE (SERGAS);FUNDACIÓN RAMÓN DOMÍNGUEZ |
发明人 |
BREA FLORIANI, José Manuel;CAMPOS PÉREZ, Francisco;CASTILLO SÁNCHEZ, José;LOZA GARCÍA, Mª Isabel;SOBRINO MOREIRAS, Tomás |
分类号 |
A61K31/19;A61K31/525;A61P9/10;A61P25/00 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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地址 |
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