VERFAHREN ZUR SYNTHESE VON BETA-LACTAMEN

摘要

It is an object of the present invention to provide a method for synthesizing beta -lactams and a method for manufacturing beta -lactams in water of high-temperature and under high-pressure, and the present invention relates to a beta -lactam synthesis method which is characterized in that beta -lactams are synthesized by reacting beta -amino acids in water at high-temperature and under high-pressure, this method being further characterized in that beta -lactams are synthesized at a high speed by cyclizing beta -amino acids in water at high-temperature and under high-pressure in which the temperature range is 200 DEG C or higher and the pressure range is 10 MPa or greater, and the present invention also relates to a method for manufacturing beta -lactams which is characterized in that beta -lactams are synthesized by reacting beta -amino acids in water at high-temperature and under high-pressure, and are then separated and purified using a column separation medium.