| 发明名称 |
2-AMINO-3, 5, 5-TRIFLUORO-3, 4, 5, 6-TETRAHYDROPYRIDINES AS BACE1 INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE |
| 摘要 |
The present invention is directed to novel inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of Aβ deposits is beneficial such as Alzheimer's disease. |
| 申请公布号 |
EP3107897(A1) |
申请公布日期 |
2016.12.28 |
| 申请号 |
EP20150707304 |
申请日期 |
2015.02.17 |
| 申请人 |
H. Lundbeck A/S |
发明人 |
JUHL, Karsten;MARIGO, Mauro;TAGMOSE, Lena;JENSEN, Thomas |
| 分类号 |
C07D211/72;A61K31/435;C07D227/10;C07D401/12;C07D405/12;C07D413/12;C07D413/14;C07D417/12 |
主分类号 |
C07D211/72 |
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