DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY

摘要

PROBLEM TO BE SOLVED: To provide a compound useful as a PPAR (peroxisome proliferator-activated receptor) agonist. SOLUTION: There is provided a compound represented by formula (I), a pharmaceutically acceptable salt or solvate thereof (wherein ring Q is an optionally substituted monocyclic or fused aryl or heteroaryl; Y1is a single bond, -NR6- or the like; ring A is an optionally substituted nonaromatic heterocyclic-diyl; the formula, -Y2Z1- is a specific binding group having N, S and O atoms; Z1is a single bond, O, S or NR9; ring B is an optionally substituted aromatic carbocyclic- or heterocyclic-diyl; Y3is a single bond, an optionally substituted lower alkylene optionally interposed by -O-, an optionally substituted lower alkenylene or the like; and Z2is COOR3or the like). COPYRIGHT: (C)2008,JPO&INPIT