COMPOSITIONS AND METHODS FOR TREATING HYPERTRIGLYCERIDEMIA
摘要
The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target ApoC3 and ANGPTL3 expression, lipid particles comprising one or more (e.g., a combination) of the therapeutic nucleic acids, and methods of delivering and/or administering the lipid particles (e.g., for treating hypertriglyceridemia in humans).
申请公布号
WO2016154127(A2)
申请公布日期
2016.09.29
申请号
WO2016US23443
申请日期
2016.03.21
申请人
PROTIVA BIOTHERAPEUTICS, INC.
发明人
CHIU, Ting;HARIHARAN, Narayanan;LEE, Amy C. H.;PASETKA, Christopher Justin;PHELPS, Janet Ruth;SNEAD, Nicholas Michael;WIECZOREK, Andrew Anthony