| 摘要 |
FIELD: medicine. ^ SUBSTANCE: there is offered enriched cell population where GABA-ergic neurons are produced by differentiation of the population of pluripotent stem cells, enriched with nestin-positive cells. The high yield of GABA-ergic neurons is caused by selection of nestin-positive cells, higher content (enrichment) of nestin-positive cells, and then further differentiation with cytosine--d-arabinofuranoside (Ara-C). ^ EFFECT: invention can be used as a source for cellular replacement therapy in neurodegenerative disorders and neural diseases. ^ 37 cl, 9 dwg, 1 tbl, 2 ex |
