发明名称 |
Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition |
摘要 |
The invention relates to the use of a pharmaceutical composition for the local treatment of a tissue infection at an infection site, the pharmaceutical composition comprising at least two different antibiotics of group A or pharmaceutically acceptable derivatives thereof, or an antibiotic of group A and at least one antibiotic of group B or pharmaceutically acceptable derivatives thereof. Group A comprises intracellular active antibiotics working as inhibitor of bacterial RNA polymerase; as inhibitor of gyrase; or as inhibitor of bacterial protein synthesis. Group B comprises extracellular active antibiotics working as inhibitor of bacterial cell wall synthesis; or inhibitor of bacterial protein synthesis; or by direct destabilisation or rupture of the bacterial cell wall. The invention further relates to a related pharmaceutical composition and a substrate carrying a pharmaceutical composition. |
申请公布号 |
AU2008280485(A1) |
申请公布日期 |
2009.01.29 |
申请号 |
AU20080280485 |
申请日期 |
2008.07.23 |
申请人 |
BIOMET DEUTSCHLAND GMBH |
发明人 |
NICOLE DUWELHENKE |
分类号 |
A61K31/4709;A61K31/65;A61K31/665;A61K31/7048;A61K31/7088;A61K38/12;A61L15/44;A61L24/00;A61L27/54;A61L31/16 |
主分类号 |
A61K31/4709 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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