| 摘要 |
The invention provides methods for the detection of apoptotic bodies in bodily fluid, including blood, blood plasma, and serum. The invention provides methods of labeling apoptotic bodies and their proteins, nucleic acids, and phospholipids. The apoptotic bodies may further be extracted, isolated, or separated from fractions of the bodily fluid. |
| 主权项 |
1. A method for extracting, isolating, or concentrating an apoptotic body present in a bodily fluid, the method comprising the steps of:
a) contacting a bodily fluid with a primer or probe specific for a protein, phospholipid, or nucleic acid present in an apoptotic body; b) conjugating or hybridizing the primer or probe to the protein, phospholipid, or nucleic acid of the apoptotic body; and c) separating the primer or probe from the bodily fluid, whereby the apoptotic body is thereupon extracted, isolated, or concentrated. |
